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Invitrogen
TOMM20L Polyclonal Antibody
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Product Details
PA5-140283
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TOMM20L. Recombinant protein control fragment (Product #RP-109553).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: AFKRRLRDKR RAEPQKAEEQ GTQLWDPTKN KKLQELFLQE VRMGELWLSR GEH
Highest antigen sequence indentity to the following orthologs: Rat - 60%, Mouse - 58%.
Target Information
The TOMM20L gene encodes a protein that is highly related to the translocase of outer mitochondria membrane 20 homolog (TOMM20), which plays a crucial role in the import of mitochondrial preproteins. TOMM20L, likely a paralog or isoform of TOMM20, shares functional similarities and contributes to the complex processes facilitating protein translocation across the outer mitochondrial membrane. This gene's product is integral to the translocase of the outer mitochondrial membrane (TOM) complex, which is essential for maintaining mitochondrial function and biogenesis. TOMM20L assists in the recognition and import of cytosolic precursor proteins into the mitochondria, influencing mitochondrial assembly and function. Although the specific functions of TOMM20L compared to TOMM20 require further elucidation, it is presumed to modulate mitochondrial dynamics and physiology. Alterations in TOMM20L expression could impact mitochondrial efficiency and are relevant in conditions related to energy metabolism and mitochondrial disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TOMM20-like protein 1; translocase of outer mitochondrial membrane 20 homolog type I; translocase of outer mitochondrial membrane 20 homolog-like
Gene Aliases: TOMM20L; UNQ9438; UNQ9438/PRO34772
UniProt ID: (Human) Q6UXN7
Entrez Gene ID: (Human) 387990
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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