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Invitrogen
TP53I11 Polyclonal Antibody
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FIGURE: 1 / 4
TP53I11 Antibody (PA5-88810) in IHC (P)
Immunohistochemistry analysis of TP53I11 in paraffin-embedded human lymph node tumors. Samples were incubated with TP53I11 Polyclonal antibody (Product # PA5-88810) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-88810
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human TP53I11 (NP_0012452491)
Conjugate
Form
Liquid
Concentration
2.69 mg/mL
Amount
269 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MAAKQPPPLM KKHSQTDLVS RLKTRKILGV GGEDDDGEVH RSKISQVLGN EIKFTIREPL GLRVWQFVSA; Positive Samples: HeLa, Mouse brain; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: p53-induced gene 11 protein; transformation related protein 53 inducible protein 11; Tumor protein p53-inducible protein 11; unnamed protein product
Gene Aliases: PIG11; TP53I11; Trp53i11
UniProt ID: (Human) O14683, (Rat) B3DMA0
Entrez Gene ID: (Human) 9537, (Rat) 311209
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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