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Product Details
PA5-41048
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.2-1 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide directed towards the N-terminal of human TPCN1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS with 2% sucrose |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2576565 |
Product Specific Information
Peptide sequence: YQEAAIYLQE GENNDKFFTH PKDAKALAAY LFAHNHLFYL MELATALLLL
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Target Information
TPCN1 may function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ20612; Two pore calcium channel protein 1; Two pore channel protein 1; two-pore channel 1; two-pore channel 1, homolog; two-pore segment channel 1; Voltage-dependent calcium channel protein TPC1
Gene Aliases: KIAA1169; TPC1; TPCN1
UniProt ID: (Human) Q9ULQ1
Entrez Gene ID: (Human) 53373
Molecular Function:
ion channel
transporter
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