Search
Proteintech
TPM1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
28477-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TPM1 fusion protein Ag29525
Conjugate
Form
Liquid
Concentration
367 µg/mL
Amount
55.05 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Tropomyosin is a dimeric coiled-coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F-actin filaments, and the lack of proline and tryptophan.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alpha tropomyosin; Alpha-tropomyosin; cardiomyopathy, hypertrophic 3; epididymis secretory protein Li 265; hepatoma alpha tropomyosin; myofibrillar protein; component of thin filaments; alternatively spliced; sarcomeric tropomyosin kappa; skeletal muscle tropomyosin; smooth muscle alpha-tropomyosin; striated muscle alpha-tropomyosin; TPM1-alpha; tropomyosin; tropomyosin 1 (alpha) isoform TPM1_1; tropomyosin 1 (alpha) isoform TPM1_2; tropomyosin 3 alpha; Tropomyosin alpha-1 chain; Tropomyosin-1; unnamed protein product
Gene Aliases: AA986836; AI854628; Alpha-tm; C15orf13; CMD1Y; CMH3; HEL-S-265; HTM-alpha; LVNC9; TM2; Tm3; Tma2; Tmpa; TMSA; Tpm-1; TPM1; Tpma
UniProt ID: (Human) P09493, (Rat) P04692, (Mouse) P58771
Entrez Gene ID: (Human) 7168, (Rat) 24851, (Mouse) 22003
actin binding
structural constituent of cytoskeleton
protein binding
cytoskeletal protein binding
structural constituent of muscle
identical protein binding
protein homodimerization activity
protein heterodimerization activity
actin filament binding
protein N-terminus binding
actin binding motor protein
positive regulation of heart rate by epinephrine
regulation of muscle contraction
cytoskeleton organization
actin filament organization
regulation of heart contraction
regulation of cell shape
muscle filament sliding
negative regulation of cell migration
ruffle organization
cellular response to reactive oxygen species
wound healing
sarcomere organization
positive regulation of cell adhesion
positive regulation of stress fiber assembly
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
negative regulation of vascular smooth muscle cell proliferation
negative regulation of vascular associated smooth muscle cell migration
in utero embryonic development
muscle contraction
positive regulation of ATPase activity
regulation of ATPase activity
actin filament capping
embryo development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support