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Bethyl Laboratories
TPR Polyclonal Antibody
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FIGURE: 1 / 3
TPR Antibody (IHC-00099) in ICC/IF
Detection of human TPR by immunocytochemistry. Sample: NBF-fixed asynchronous HeLa cells. Antibody: Affinity purified rabbit anti-TPR (Product # IHC-00099) used at a dilution of 1:250. Detection: Green-fluorescent Anti-rabbit IgG FITC conjugated (A120-501F) used at a dilution of 1:100.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
IHC-00099
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 2300 and the C-terminus (residue 2349) of Human Translocated Promoter Region Protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
25 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Rabbit, Pig, Panda, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Little brown bat
Target Information
Steroidogenic factor-1 (SF-1) regulates multiple genes involved in the adrenal and gonadal development and in the biosynthesis of a variety of hormones, including adrenal and gonadal steroids, anti-Mullerian hormone (AMH), and gonadotropins. SF-1 belongs to the fushi tarazu factor-1 (FTZ-F1) subfamily of orphan nuclear receptors. In the adult ovary, SF-1 localizes to theca/interstitial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: megator; NPC-associated intranuclear protein; nuclear pore complex-associated protein TPR; Tpr; TPR; nuclear pore complex-associated protein; translocated promoter region (to activated MET oncogene); translocated promoter region and nuclear basket protein; translocated promoter region protein; tumor potentiating region; unnamed protein product
Gene Aliases: 2610029M07Rik; MRT79
UniProt ID: (Human) P12270, (Mouse) F6ZDS4
Entrez Gene ID: (Human) 7175, (Mouse) 108989
negative regulation of transcription from RNA polymerase II promoter
RNA import into nucleus
RNA export from nucleus
mRNA export from nucleus
protein import into nucleus
protein export from nucleus
intracellular protein transport
nucleocytoplasmic transport
nuclear pore organization
mitotic spindle assembly checkpoint
regulation of mRNA export from nucleus
regulation of mitotic sister chromatid separation
positive regulation of heterochromatin assembly
regulation of protein stability
mRNA export from nucleus in response to heat stress
regulation of protein localization
cellular response to heat
cellular response to interferon-alpha
regulation of protein import into nucleus
positive regulation of protein import into nucleus
nuclear matrix organization
negative regulation of translational initiation
positive regulation of nucleocytoplasmic transport
regulation of protein export from nucleus
positive regulation of protein export from nucleus
negative regulation of RNA export from nucleus
nuclear export
nuclear pore complex assembly
response to epidermal growth factor
positive regulation of mitotic cell cycle spindle assembly checkpoint
positive regulation of intracellular protein transport
regulation of mitotic spindle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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