Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: DRDRRRVKN GEHSWDLDRE KNREHDKPEK KSASSGEMSK KLSDGTFKDS KAETETEIST RASKSLTTKT SKRRSKNSVE GDSTSDAEGD AGPAGQDKSE VPETPEIPNE LSSNIRRIPR PGSARPAPPR VKRQDSMEAL QMDRSGSGKT VSNVITESHN SDNEEDDQFV VEAAPQLSEM SEIEMVTAVE LEEEEKHGGL VKKILETKKD YEKLQQSPKP GEKERSLFES AWKKEKDIVS KEIEKLRTSI QTLCKSALPL GKIMDYIQED VDAMQNELQM WHSENRQHAE ALQQEQRITD CAVEPLKAEL AELEQLIKDQ QDKICAVKAN ILKNEEKIQK MVYSINLTSR R (276-626 aa encoded by BC059174)
Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation and apoptosis in various types of cells. TNFR-associated factors (TRAFs) are a family of proteins that were initially discovered as downstream signal transducers of the TNFR superfamily. TRAF3 contains an N-terminal ring finger/zinc finger region that is thought to be essential for downstream signaling. MIP-T3 is associated with TRAF3. MIP-T3 binds to taxol-stabilized microtubules and to tubulin in vitro, and MIP-T3 recruits TRAF3 to microtubules when both proteins are overexpressed. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3. This interaction may provide a novel mechanism in sequestering TRAF3 to the cytoskeletal network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: interleukin 13 receptor alpha 1-binding protein-1; Interleukin-13 receptor alpha 1-binding protein 1; Intraflagellar transport protein 54 homolog; microtubule interacting protein that associates with TRAF3; Microtubule-interacting protein associated with TRAF3; microtubule-interacting protein that associates with TRAF3; MIP-T3; TNF receptor-associated factor 3 interacting protein 1; TRAF3-interacting protein 1
Gene Aliases: 3930402D05Rik; AU041749; IFT54; MIP-T3; MIPT3; SLSN9; TRAF3IP1
UniProt ID: (Human) Q8TDR0, (Rat) Q5XIN3, (Mouse) Q149C2
Entrez Gene ID: (Human) 26146, (Rat) 363286, (Mouse) 74019
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support