|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 223 of Human TRAF3IP1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
PA5-30507 targets TRAF3IP1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30507 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 223 of Human TRAF3IP1.
Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome.
PA5-30507 was used in immunocytochemistry to report the importance of DYNC2LI1 in dynein-2 complex stability, cilium function, Hedgehog regulation and skeletogenesis.
|Taylor SP,Dantas TJ,Duran I,Wu S,Lachman RS,Nelson SF,Cohn DH,Vallee RB,Krakow D||Nature communications (6:null)||2015|