|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues L(380) G E R L A K Q K I E D H L L S S G K(398) of human TRICK2.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4365 detects the TRICK2 protein in human samples.
PA1-4365 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~26 kDa protein representing TRICK2 in transfected 293T cells.
The PA1-4365 immunogen is a synthetic peptide corresponding to residues L(380) G E R L A K Q K I E D H L L S S G K(398) of human TRICK2.
A subset of the tumor necrosis factor (TNF) receptor family contain a conserved intracellular motif, the death domain. A member of this family, TRICK2, the TRAIL (TNF-related apoptosis-inducing ligand) receptor inducer of cell killing 2) is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen. TRICK2, like DR4, is a receptor for TRAIL/APO-2L [2,3] and could inhibit TRAIL-induced killing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.