The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.
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Protein Aliases: DKFZp781N23103; Signal sequence receptor subunit alpha; signal sequence receptor, alpha; SSR alpha subunit; SSR-alpha; translocon-associated protein alpha subunit; Translocon-associated protein subunit alpha; TRAP alpha; TRAP-alpha
Gene Aliases: PSEC0262; SSR1; TRAPA
UniProt ID: (Human) P43307
Entrez Gene ID: (Human) 6745
Molecular Function: membrane traffic protein