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Product Details
27549-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TRAPPC10 fusion protein Ag26900
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: IVENDAKKKN KTNILPRTSI VDKIRNDFCN KQSDRCVVLS DPLKDSSRTQ ESWNAFLTKL RTLLLMSFTK NLGKFEDDMR TLREKRTEPG WSFCEYFMVQ EELAFVFEML QQFEDALVQY DELDALFSQY VVNFGAGDGA NWLTFFCQPV KSWNGLILRK PIDMEKRESI QRREATL
Target Information
TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein) or GT334, is a widely expressed 1,259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein and its structure and function appears to be conserved. Localizing to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Mutations in the gene encoding TRAPPC10 may be involved in autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive type of progressive myoclonic epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EHOC-1; Epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; Protein GT334; Trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 130; Trafficking protein particle complex subunit TMEM1; transmembrane protein 1; Transport protein particle subunit TMEM1; TRAPP 130 kDa subunit; TRAPP subunit TMEM1
Gene Aliases: B230307C21Rik; EHOC-1; EHOC1; Gm870; GT334; TMEM1; TRAPPC10; TRS130; TRS30
UniProt ID: (Human) P48553, (Mouse) Q3TLI0
Entrez Gene ID: (Human) 7109, (Mouse) 216131, (Rat) 309678
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