Search
Invitrogen
TRF1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-18010
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (TMKKLKLISSDSED) corresponding to the C-terminus amino acids of TERF1 (aa 426-439).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: alternatively spliced; telomeric protein; FLJ41416; NIMA-interacting protein 2; Telomeric protein Pin2/TRF1; telomeric repeat binding factor (NIMA-interacting) 1; Telomeric repeat-binding factor 1; TTAGGG repeat-binding factor 1; unnamed protein product
Gene Aliases: hTRF1-AS; PIN2; t-TRF1; TERF1; TRBF1; TRF; TRF1
UniProt ID: (Human) A7XP29
Entrez Gene ID: (Human) 7013
telomere maintenance
telomere maintenance via telomerase
negative regulation of DNA replication
response to xenobiotic stimulus
telomere capping
positive regulation of telomere maintenance
negative regulation of telomere maintenance via telomerase
negative regulation of telomere maintenance via semi-conservative replication
meiotic telomere clustering
cell division
telomeric D-loop disassembly
t-circle formation
negative regulation of telomere maintenance via telomere lengthening
positive regulation of telosome assembly
negative regulation of establishment of protein localization to telomere
negative regulation of establishment of RNA localization to telomere
negative regulation of establishment of macromolecular complex localization to telomere
negative regulation of telomeric D-loop disassembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support