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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from residues 250 - 350 of Human TRF2.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1 µg/ml|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-19426 targets TRF2 in IF and WB applications and shows reactivity with Human samples.
The PA5-19426 immunogen is synthetic peptide derived from residues 250 - 350 of Human TRF2.
PA5-19426 detects TRF2 which has a predicted molecular weight of approximately 65 kDa and 69 kDa.
Store antibody at 4°C for 1-2 weeks. For long-term storage, store at -20°C.
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Telomeric DNA-binding protein; telomeric repeat binding protein 2; Telomeric repeat-binding factor 2; TRBF2, TRF2, TTAGGG repeat-binding factor 2; TTAGGG repeat-binding factor 2
TERF2; TRBF2; TRF2