Immunogen sequence: PNPLSSPHLY HKQHNGMKLS MKGSHGHTQG GGYSSVGSGG VRPPVGNRGH HQYNRTGWRR KKHTHTRDSL PVSLSR
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
TRF4-1 is a nuclear protein whose expression is cell cycle-regulated at a post-transcriptional level. Two genes, TRF4-1 and TRF4-2, belonging to this family have been identified. TRF4 is also required to maintain a different aspect of higher order chromosome structure, sister chromatid cohesion.
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Protein Aliases: DNA polymerase kappa; DNA polymerase sigma; LAK-1; LAK1; Non-canonical poly(A) RNA polymerase PAPD7; PAP-associated domain-containing protein 7; POLK; POLS; polymerase (DNA directed) sigma; polymerase (DNA-directed) sigma; Terminal guanylyltransferase; Terminal nucleotidyltransferase 4A; Terminal uridylyltransferase 5; Topoisomerase-related function protein 4-1; TRAMP-like complex polyadenylate polymerase; TRF4; TRF4-1; TRF41; TUTase 5; TUTASE5
Gene Aliases: LAK-1; LAK1; PAPD7; POLK; POLS; TENT4A; TRF4; TRF4-1; TRF41; TUTASE5