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Invitrogen
TRH Polyclonal Antibody
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Product Details
PA5-89851
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 143-242 of human TRH (NP_0090481)
Conjugate
Form
Liquid
Concentration
0.58 mg/mL
Amount
58 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: U-87MG, BXPC-3, A-549, DU145, Mouse brain, Rat testis
Immunogen sequence: WLAYAVPKRQ HPGRRLADPK AQRSWEEEEE EEEREEDLMP EKRQHPGKRA LGGPCGPQGA YGQAGLLLGL LDDLSRSQGA EEKRQHPGRR AAWVREPLEE
Target Information
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin; protirelin; thyrotropin releasing hormone; thyrotropin-releasing factor; TSH-releasing factor; unnamed protein product
Gene Aliases: Pro-TRH; THR; TRF; TRH; TRH01
UniProt ID: (Human) P20396, (Rat) P01150, (Mouse) Q62361
Entrez Gene ID: (Human) 7200, (Rat) 25569, (Mouse) 22044
histamine metabolic process
signal transduction
cell-cell signaling
adult walking behavior
hormone-mediated signaling pathway
negative regulation of glutamate secretion
positive regulation of gamma-aminobutyric acid secretion
positive regulation of insulin secretion
eating behavior
response to hypoxia
response to cold
response to glucose
response to organic cyclic compound
response to ethanol
response to corticosterone
negative regulation of feeding behavior
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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