Immunogen sequence: QPEAAQQEAV TAAEHPGLDD FLRQVERLLF LRENIQRLQG DQGEHSASQI FQSDWLSKRQ HPGKREEEEE EGVEEEEEEE GGAVGPHKRQ HPGRREDEAS WSVDVTQHKR QHPGRRSPWL AYAVPKRQHP GRRLADPKAQ RSWEEEEEEE EREEDLMPEK RQHPGKRALG GPCGPQGAYG QAGLLLGLLD DLSRSQGAEE KRQHPG; Positive Samples: SH-SY5Y, Mouse brain
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin; Protirelin; Thyroliberin; thyrotropin releasing hormone; Thyrotropin-releasing factor; Thyrotropin-releasing hormone; TRF; TRH; TSH-releasing factor
Gene Aliases: Pro-TRH; TRF; TRH