This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 5
Immunogen sequence: RQDKMYSYSS DHTRVDEYYI EDTPIYGNLD DMISEPMDEN CYEQMKARPE KSVNKMQEAT PSAQATNETQ MCYASLDHSV KGKRRKPRKQ NTHFSDKDGD EQLHAI
Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 58%.
TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: pp29/30; T cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TRIM
Gene Aliases: HSPC062; pp29/30; TCRIM; TRAT1; TRIM
UniProt ID: (Human) Q6PIZ9
Entrez Gene ID: (Human) 50852
Molecular Function: defense/immunity protein