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TRIM13 Polyclonal Antibody
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Product Details
BS-6395R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human TRIM13/LEU5, amino acids 151-250.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by the RFP2 gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies near the nucleus, but its function is unknown. The gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-cell chronic lymphocytic leukemia tumor suppressor Leu5; CLL-associated RING finger; E3 ubiquitin-protein ligase TRIM13; Leukemia-associated protein 5; putative E3 ubiquitin-protein ligase; RFP2; putative tumor suppressor; putative transcription factor; Putative tumor suppressor RFP2; RBBC protein; RBCC protein; Ret finger protein 2; RING finger protein 77; RING-type E3 ubiquitin transferase TRIM13; tripartite motif protein 13; tripartite motif-containing 13; Tripartite motif-containing protein 13; unnamed protein product
Gene Aliases: 3110001L12Rik; CAR; DLEU5; LEU5; RFP2; RNF77; TRIM13
UniProt ID: (Human) O60858, (Mouse) Q9CYB0, (Rat) Q5M7V1
Entrez Gene ID: (Human) 10206, (Mouse) 66597, (Rat) 364398
transcription coactivator activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
transferase activity
metal ion binding
ubiquitin protein ligase activity
ubiquitin-like protein ligase activity
signal transducer activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
immune system process
positive regulation of macroautophagy
protein ubiquitination
negative regulation of viral transcription
ERAD pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation by host of viral release from host cell
innate immune response
positive regulation of transcription, DNA-templated
protein autoubiquitination
endoplasmic reticulum mannose trimming
signal transduction
positive regulation of cell death
ER-associated ubiquitin-dependent protein catabolic process
positive regulation of NF-kappaB transcription factor activity
negative regulation of viral release from host cell
response to gamma radiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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