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TRIM15 Antibody (PA5-28729) in WB
Western Blot analysis of TRIM15 expression in transfected 293T cell line by TRIM15 polyclonal antibody. Lane A: Non-transfected lysate. Lane B: TRIM15 transfected lysate. 7.5% SDS PAGE. TRIM15 Polyclonal Antibody (Product # PA5-28729) diluted at 1:500.
Product Details
PA5-28729
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 1 and 46 of Human RNF93
Conjugate
Form
Liquid
Concentration
0.59 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546205
Product Specific Information
Recommended positive controls: RNF93 tansfected 293T cell.
Predicted reactivity: Chimpanzee (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM15; RING finger protein 93; tripartite motif-containing 15; Zinc finger protein 178; Zinc finger protein B7
Gene Aliases: RNF93; TRIM15; ZNF178; ZNFB7
UniProt ID: (Human) Q9C019
Entrez Gene ID: (Human) 89870
mesodermal cell fate determination
positive regulation of type I interferon production
innate immune response
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
positive regulation of RIG-I signaling pathway
negative regulation of intracellular transport of viral material
negative regulation of viral release from host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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