Immunogen sequence: CDFCLDDTRR VKAVKSCLTC MVNYCEEHLQ PHQVNIKLQS HLLTEPVKDH NWRYCPAHHS PLSAFCCPDQ QCICQDCCQE HSGHTIVSLD AARRDKEAEL QCTQLDLERK LKLNENAISR LQANQKSVLV SVSEVKAVAE MQFGE
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 74%.
This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined.
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Protein Aliases: E3 ubiquitin-protein ligase TRIM16; Estrogen-responsive B box protein; tripartite motif-containing 16; Tripartite motif-containing protein 16
Gene Aliases: EBBP; TRIM16
UniProt ID: (Human) O95361
Entrez Gene ID: (Human) 10626