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Proteintech
TRIM23 Polyclonal Antibody
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Product Details
12607-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TRIM23 Fusion Protein Ag3302 (275-574 aa encoded by BC022510)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EHVPGTAEN ARSCIRAYFY DLHETLCRQE EMALSVVDAH VREKLIWLRQ QQEDMTILLS EVSAACLHCE KTLQQDDCRV VLAKQEITRL LETLQKQQQQ FTEVADHIQL DASIPVTFTK DNRVHIGPKM EIRVVTLGLD GAGKTTILFK LKQDEFMQPI PTIGFNVETV EYKNLKFTIW DVGGKHKLRP LWKHYYLNTQ AVVFVVDSSH RDRISEAHSE LAKLLTEKEL RDALLLIFAN KQDVAGALSV EEITELLSLH KLCCGRSWYI QGCDARSGMG LYEGLDWLSR QLVAAGVLDV A (275-574 aa encoded by BC022510)
Target Information
Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor domain protein 1, 64kD; ADP-ribosylation factor domain protein 1, 64kDa; ADP-ribosylation factor domain-containing protein 1; ARF domain protein 1; E3 ubiquitin-protein ligase TRIM23; GTP-binding protein ARD-1; RING finger protein 46; RING-type E3 ubiquitin transferase TRIM23; tripartite motif protein 23; tripartite motif protein TRIM23; tripartite motif-containing 23; Tripartite motif-containing protein 23
Gene Aliases: 6330516O20Rik; AI450195; ARD1; ARFD1; RNF46; TRIM23
UniProt ID: (Human) P36406
Entrez Gene ID: (Human) 373, (Mouse) 81003
GTPase activity
ubiquitin-protein transferase activity
protein binding
GTP binding
enzyme activator activity
zinc ion binding
ligase activity
GDP binding
identical protein binding
nucleotide binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
G-protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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