|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 218 of Human TRIM27|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Contains||0.025% ProClin 300|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27603 targets TRIM27 in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-27603 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 218 of Human TRIM27.
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ret finger protein; RFP transforming protein; RING finger protein 76; RING-type E3 ubiquitin transferase TRIM27; RNF76; tripartite motif protein 27; tripartite motif protein TRIM27; tripartite motif-containing 27; Tripartite motif-containing protein 27; Zinc finger protein RFP
Gene Aliases: AW538890; Gm19403; RFP; RNF76; TRIM27
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