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Proteintech

TRIM32 Polyclonal Antibody

3 References
View all (7) TRIM32 antibodies
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Product Details

10326-1-AP

Applications Tested Dilution Publications

Western Blot (WB)

 1:500-1:1,000 View 2 publications 2 publications

Immunohistochemistry (IHC)

 - View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

 1:20-1:200 -

Immunohistochemistry (PFA fixed) (IHC (PFA))

 1:20-1:200 -

Immunocytochemistry (ICC/IF)

 1:20-1:200 -
Product Specifications

Species Reactivity

 Human, Mouse, Rat

Published species

 Human, Mouse

Host/Isotype

 Rabbit / IgG

Class

 Polyclonal

Type

 Antibody

Immunogen

TRIM32 Fusion Protein Ag0401 (111-430 aa encoded by BC003154)
View antigen

Conjugate

 Unconjugated

Form

 Liquid

Concentration

 0.3 mg/mL

Purification

 Antigen affinity chromatography

Storage buffer

 PBS, pH 7.3, with 50% glycerol

Contains

 0.1% sodium azide

Storage conditions

 -20°C

Product Specific Information

Immunogen sequence: FCRSCGLVL CEPCREADHQ PPGHCTLPVK EAAEERRRDF GEKLTRLREL MGELQRRKAA LEGVSKDLQA RYKAVLQEYG HEERRVQDEL ARSRKFFTGS LAEVEKSNSQ VVEEQSYLLN IAEVQAVSRC DYFLAKIKQA DVALLEETAD EEEPELTASL PRELTLQDVE LLKVGHVGPL QIGQAVKKPR TVNVEDSWAM EATASAASTS VTFREMDMSP EEVVASPRAS PAKQRGPEAA SNIQQCLFLK KMGAKGSTPG MFNLPVSLYV TSQGEVLVAD RGNYRIQVFT RKGFLKEIRR SPSGIDSFVL SFLGADLPNL T (111-430 aa encoded by BC003154)

Target Information

TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 72 kDa Tat-interacting protein; bM468K2.2 (tripartite motif protein 32); E3 ubiquitin-protein ligase TRIM32; RING-type E3 ubiquitin transferase TRIM32; RP11-67K19.1; TAT-interactive protein, 72-KD; tripartite motif protein 32; tripartite motif-containing 32; Tripartite motif-containing protein 32; zinc finger protein 117; Zinc finger protein HT2A; zinc-finger protein HT2A

Gene Aliases: 1810045E12Rik; 3f3; BBS11; HT2A; LGMD2H; TATIP; TRIM32; Zfp117

UniProt ID: (Human) Q13049, (Mouse) Q8CH72

Entrez Gene ID: (Human) 22954, (Mouse) 69807, (Rat) 313264

Function(s)
protein polyubiquitination tissue homeostasis actin ubiquitination response to UV protein ubiquitination positive regulation of cell growth positive regulation of cell migration regulation of type I interferon production negative regulation of viral transcription response to tumor necrosis factor protein ubiquitination involved in ubiquitin-dependent protein catabolic process positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response fat cell differentiation positive regulation of neuron differentiation positive regulation of protein catabolic process positive regulation of cell cycle positive regulation of proteolysis muscle cell cellular homeostasis negative regulation of fibroblast proliferation positive regulation of neurogenesis positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of striated muscle cell differentiation axon development negative regulation of viral release from host cell negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage positive regulation of tumor necrosis factor-mediated signaling pathway positive regulation of interleukin-17-mediated signaling pathway positive regulation of chemokine (C-C motif) ligand 20 production positive regulation of cell motility negative regulation of keratinocyte apoptotic process biological_process
Process(es)
transcription coactivator activity RNA binding ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity myosin binding Tat protein binding translation initiation factor binding ubiquitin binding protein self-association ubiquitin protein ligase activity UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ribosomal S6-glutamic acid ligase activity coenzyme F420-0 gamma-glutamyl ligase activity coenzyme F420-2 alpha-glutamyl ligase activity metal ion binding protein-glycine ligase activity protein-glycine ligase activity, initiating protein-glycine ligase activity, elongating tubulin-glycine ligase activity protein-glutamic acid ligase activity tubulin-glutamic acid ligase activity molecular_function

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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