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Product Details
13037-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TRIM37 Fusion Protein Ag3690 (122-450 aa encoded by BC036012)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GMHGGHTFK PLAEIYEQHV TKVNEEVAKL RRRLMELISL VQEVERNVEA VRNAKDERVR EIRNAVEMMI ARLDTQLKNK LITLMGQKTS LTQETELLES LLQEVEHQLR SCSKSELISK SSEILMMFQQ VHRKPMASFV TTPVPPDFTS ELVPSYDSAT FVLENFSTLR QRADPVYSPP LQVSGLCWRL KVYPDGNGVV RGYYLSVFLE LSAGLPETSK YEYRVEMVHQ SCNDPTKNII REFASDFEVG ECWGYNRFFR LDLLANEGYL NPQNDTVILR FQVRSPTFFQ KSRDQHWYIT QLEAAQTSYI QQINNLKERL TIELSRTQKS (122-450 aa encoded by BC036012)
Target Information
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate (PIP). PI4KB may regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM37; Mulibrey nanism protein; RING-B-box-coiled-coil protein; RING-type E3 ubiquitin transferase TRIM37; TRAF encompassing factor 3; Tripartite motif-containing protein 37
Gene Aliases: 1110032A10Rik; 2810004E07Rik; AI848587; AU043018; KIAA0898; mKIAA0898; MUL; POB1; TEF3; TRIM37
UniProt ID: (Human) O94972, (Mouse) Q6PCX9
Entrez Gene ID: (Human) 4591, (Mouse) 68729
chromatin binding
ubiquitin-protein transferase activity
tumor necrosis factor receptor binding
protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase binding
protein homodimerization activity
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
protein modifying enzyme
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of NF-kappaB transcription factor activity
histone H2A monoubiquitination
histone H2A-K119 monoubiquitination
negative regulation of centriole replication
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
aggresome assembly
Performance Guarantee
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