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Invitrogen
TRIM38 Polyclonal Antibody
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Product Details
PA5-83204
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TRIM38. Recombinant protein control fragment (Product #RP-91652).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LHEEEKSYLW RLEKEEQQTL SRLRDYEAGL GLKSNELKSH ILELEEKCQG SAQKLLQNVN DTLSRSWAVK LETSEAVSLE LHTMCNVSKL YFDVKKMLRS HQVSVTLDPD TAHHELILSE DRRQVTRGYT QENQDTSSRR FTA
Highest antigen sequence indentity to the following orthologs: Mouse - 50%, Rat - 44%.
Target Information
This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM38; MGC8946; RING finger protein 15; Ro/SSA ribonucleoprotein homolog; Tripartite motif-containing protein 38; Zinc finger protein RoRet
Gene Aliases: RNF15; RORET; TRIM38
UniProt ID: (Human) O00635
Entrez Gene ID: (Human) 10475
regulation of interferon-beta production
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of viral genome replication
positive regulation of viral entry into host cell
negative regulation of defense response to virus
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
interferon-gamma-mediated signaling pathway
protein K48-linked ubiquitination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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