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Product Details
PA5-98215
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
ELISA (ELISA) |
Assay-Dependent | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant Human E3 ubiquitin-protein ligase TRIM38 protein (45-259AA) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
4 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.03% ProClin 300 |
Storage conditions |
-20°C or -80°C if preferred |
RRID |
AB_2812828 |
Target Information
This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM38; MGC8946; RING finger protein 15; Ro/SSA ribonucleoprotein homolog; Tripartite motif-containing protein 38; Zinc finger protein RoRet
Gene Aliases: RNF15; RORET; TRIM38
UniProt ID: (Human) O00635
Entrez Gene ID: (Human) 10475
Molecular Function:
ubiquitin-protein ligase
regulation of interferon-beta production
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of viral genome replication
positive regulation of viral entry into host cell
negative regulation of defense response to virus
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
interferon-gamma-mediated signaling pathway
protein K48-linked ubiquitination
Performance Guarantee
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