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Immunogen sequence: LLPCLHTVCTT CLEQLEPFSV VDIRGGDSDT SSEGSIFQEL KPRSLQSQIG ILCPVCDAQV DLPMGGVKAL TIDHLAVNDV MLE
Highest antigen sequence identity to the following orthologs - mouse 85%, rat 87%.
TRIM45 is a member of the tripartite motif family. It may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described. TRIM45 belongs to a family of tripartite motif (TRIM) proteins that play important roles in a variety of cellular functions, including cell proliferation, differentiation, development, oncogenesis, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin-protein ligase TRIM45; FLJ13181; RING finger protein 99; tripartite motif-containing 45
Gene Aliases: RNF99; TRIM45
UniProt ID: (Human) Q9H8W5
Entrez Gene ID: (Human) 80263
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