Immunogen sequence: IAMLVAGND RVQAVITQME EVCQTIEDNS RRQKQLLNQR FESLCAVLEE RKGELLQALA REQEEKLQRV RGLIRQYGDH LEASSKLVES AIQSMEEPQM ALYLQQAKEL INKVGAMSKV ELAGRPEPGY ESMEQFTVRV EHVAEMLRTI DFQPGASGEE EEVAPDGEEG SAGPEEERPD GP (178-358 aa encoded by BC141807)
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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Protein Aliases: MuRF; MuRF-3; Muscle-specific RING finger protein; Muscle-specific RING finger protein 3; muscle-specific RING-finger protein; muscle-specific RING-finger protein 3; OTTHUMP00000122598; RING finger protein 30; tripartite motif-containing 54; Tripartite motif-containing protein 54
Gene Aliases: 4930486E09Rik; 4930566I02Rik; MURF; MURF-3; MURF3; RNF30; TRIM54
Molecular Function: ubiquitin-protein ligase