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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
TRIM6 Fusion Protein Ag2556 (96-395 aa encoded by BC065575) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.22 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: QLRNILDRV EQRELKKLEQ EEKKGLRIIE EAENDLVHQT QSLRELISDL ERRCQGSTME LLQDVSDVTE RSEFWTLRKP EALPTKLRSM FRAPDLKRML RVCRELTDVQ SYWVDVTLNP HTANLNLVLA KNRRQVRFVG AKVSGPSCLE KHYDCSVLGS QHFSSGKHYW EVDVAKKTAW ILGVCSNSLG PTFSFNHFAQ NHSAYSRYQP QSGYWVIGLQ HNHEYRAYED SSPSLLLSMT VPPRRVGVFL DYEAGTVSFY NVTNHGFPIY TFSKYYFPTT LCPYFNPCNC VIPMTLRRPS S (96-395 aa encoded by BC065575)
TRIM6 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A read-through transcript transcribed from this gene and TRIM34 has been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RING finger protein 89; RING-type E3 ubiquitin transferase TRIM6; tripartite motif protein 6; tripartite motif-containing 6; Tripartite motif-containing protein 6
Gene Aliases: C430046K18Rik; D7Ertd684e; RNF89; TRIM6
UniProt ID: (Human) Q9C030, (Mouse) Q8BGE7
Entrez Gene ID: (Human) 117854, (Rat) 293294, (Mouse) 94088
Molecular Function:
ubiquitin-protein ligase
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