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Antibody detects endogenous levels of total TRIM68.
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.
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Protein Aliases: E3 ubiquitin-protein ligase TRIM68; FLJ10369; MGC126176; RING finger protein 137; RING-type E3 ubiquitin transferase TRIM68; Ro/SSA1 related protein; SS-56; SSA protein SS-56; Tripartite motif-containing protein 68
Gene Aliases: GC109; RNF137; SS-56; SS56; TRIM68
UniProt ID: (Human) Q6AZZ1
Entrez Gene ID: (Human) 55128
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