|Tested species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide from the 4th cytoplasmic loop of rat TRPC4 conjugated to an immunogenic carrier protein|
|Purification||Ammonium sulfate precipitation|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||10-50 µg/ml|
|Western Blot (WB)||10-50 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Reconstitute with 500 ul of distilled water.
Centrifuge to remove any insoluble material.
Thought to form non-selective a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. Isoform alpha but not isoform beta associates with inositol-1,4,5-triphosphate receptor (ITPR). Interacts with NHERF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.