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TRPC4AP Polyclonal Antibody
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Product Details
OST00242W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from the c-terminal region of human TRPC4AP (TRUSS) conjugated to an immunogenic carrier protein was used as the immunogen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen is homologous in rat and mouse.
Specificity of this antibody: TRPC4AP.
Target Information
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: protein phosphatase 1, regulatory subunit 158; Protein TAP1; Protein TRUSS; Rabex-5/Rin2-interacting protein; Short transient receptor potential channel 4-associated protein; TAP1 protein; TNF-receptor; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP; transient receptor protein 4, associated protein; TRP4-associated protein; Trp4-associated protein TAP1; trpc4-associated protein; tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein; unnamed protein product
Gene Aliases: 4833429F06Rik; C20orf188; D2Ertd113e; mFLJ00177; PPP1R158; TRPC4AP; TRRP4AP; TRUSS
UniProt ID: (Human) Q8TEL6, (Mouse) Q9JLV2
Entrez Gene ID: (Human) 26133, (Rat) 362247, (Mouse) 56407
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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