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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (EKLSMEPNQEETNR) corresponding to the C-terminus amino acids of TRPC6|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.03-0.1 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine based on sequence homology.
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential channel 6; transient receptor protein 6; TRP-6; TRP6; TRPC6
FSGS2; TRP6; TRPC6