|Western Blot (WB)||0.03-0.1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (EKLSMEPNQEETNR) corresponding to the C-terminus amino acids of TRPC6|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine based on sequence homology.
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; Short transient receptor potential channel 6; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential channel 6; Transient receptor protein 6; TRP-6; TRP6; TRPC6
Gene Aliases: FSGS2; TRP6; TRPC6
UniProt ID: (Human) Q9Y210
Entrez Gene ID: (Human) 7225
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