|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a portion of the human transient receptor potential cation channel, subfamily M, member 2 encoded within exon 13.|
|Purification||Antigen affinity chromatography|
|Storage buffer||citric acid, pH 7-8|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||1-4 µg/mg of lysate|
|Western Blot (WB)||1:300|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-24996 detects TRPM2 from human samples.
PA1-24996 has been successfully used in immunoprecipitation, and Western blot procedures.
The PA1-24996 immunogen is a synthetic peptide corresponding to a portion of the human transient receptor potential cation channel, subfamily M, member 2 encoded within exon 13.
The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.