Reconstitute with 100 µL of distilled water.
This gene encodes a member of the transient receptor potential protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Caions. It is activated by lower concentrations of intracellular Ca, and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15. 5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
Protein Aliases: Long transient receptor potential channel 5; LTrpC-5; MLSN1 and TRP-related; MLSN1- and TRP-related gene 1 protein; Transient receptor potential cation channel subfamily M member 5; transient receptor potential cation channel, subfamily M, member 5; TRPM5
Gene Aliases: LTRPC5; MTR1; TRPM5
UniProt ID: (Human) Q9NZQ8
Entrez Gene ID: (Human) 29850