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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human TRPM7 (CHAK1)|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ChaK; channel-kinase 1; long transient receptor potential channel 7; LTRPC ion channel family member 7; LTRPC7; transient receptor potential cation channel, subfamily M, member 7; transient receptor potential-phospholipase C-interacting kinase; TRP-PLIK; TRPM7
ALSPDC; CHAK; CHAK1; LTrpC-7; LTRPC7; TRP-PLIK; TRPM7