|Tested species reactivity||Zebrafish|
|Published species reactivity||Zebrafish|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide from zebrafish trpv4, conjugated to an immunogenic carrier protein|
|Purification||Ammonium sulfate precipitation|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||10-50 µg/ml|
|Western Blot (WB)||10-50 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
Reconstitute with 500 ul of distilled water.
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity.
OST00072G was used in immunohistochemistry to report that osmotic stress regulates the activation of immunity in neonatal zebrafish
|Galindo-Villegas J,Montalban-Arques A,Liarte S,de Oliveira S,Pardo-Pastor C,Rubio-Moscardo F,Meseguer J,Valverde MA,Mulero V||Journal of immunology (Baltimore, Md. : 1950) (196:738)||2016|