TRSPAP1 is involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. It stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. It may be involved in the methylation of tRNA(Sec) and enhances efficiency of selenoproteins synthesis.
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Protein Aliases: FLJ20503; RP4-669K10.4; SECp43; tRNA selenocysteine 1-associated protein 1; tRNA selenocysteine associated protein (SECP43); tRNA selenocysteine associated protein 1; tRNA selenocysteine-associated protein 1
Gene Aliases: PRO1902; SECP43; TRNAU1AP; TRSPAP1
UniProt ID: (Human) Q9NX07
Entrez Gene ID: (Human) 54952