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Product Details
H00079042-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TSEN34 (AAH00944.1, 1 a.a. approximately 390 a.a) full-length human protein.
Conjugate
Unconjugated
Form
Liquid
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLVVEVANGR SLVWGAEAVQ ALRERLGVGG RTVGALPRGP RQNSRLGLPL LLMPEEARLL AEIGAVTLVS APRPDSRHHS LALTSFKRQQ EESFQEQSAL AAEARETRRQ EVLEKITEGQ AAKKQKLEQA SGASSSQEAG SSQAAKEDET SDGQASGEQE EAGPSSSQAG PSNGVAPLPR SALLVQLATA RPRPVKARPL DWRVQSKDWP HAGRPAHELR YSIYRDLWER GFFLSAAGKF GGDFLVYPGD PLRFHAHYIA QCWAPEDTSH SKTWLLLGAL EPASERPCSS VLRSLMVRWS TPPCNGPACS ELQRPRGCGC VGSKSLSGCS PALLWESRTS SYLSPRLVFD SRFSNTTSFL CSSLFQSTYW LCFCSYLFSH CELPENGAWV
Target Information
TSEN34 encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CTD-3093M3.1; HsSen34; leukocyte receptor cluster (LRC) member 5; Leukocyte receptor cluster member 5; tRNA-intron endonuclease Sen34; tRNA-splicing endonuclease subunit Sen34; TSEN34 tRNA splicing endonuclease subunit
Gene Aliases: LENG5; PCH2C; SEN34; SEN34L; TSEN34
UniProt ID: (Human) Q9BSV6
Entrez Gene ID: (Human) 79042
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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