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Bioss
TSHR Polyclonal Antibody
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Product Details
BS-2087R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human TSHR, amino acids 201-300.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
TSH Receptor gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC141920; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2; Thyroid-stimulating hormone receptor; Thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; TSH-R
Gene Aliases: AI481368; CHNG1; hTSHR-I; hypothroid; hyt; LGR3; pet; TSHR
UniProt ID: (Human) P16473, (Mouse) P47750
Entrez Gene ID: (Human) 7253, (Mouse) 22095
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
cell-cell signaling
nervous system development
positive regulation of cell proliferation
hormone-mediated signaling pathway
thyroid-stimulating hormone signaling pathway
signal transduction
adult locomotory behavior
B cell differentiation
regulation of locomotion
positive regulation of multicellular organism growth
inner ear receptor cell development
inner ear receptor stereocilium organization
dopaminergic neuron differentiation
cochlea morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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