|Immunocytochemistry (ICC)||2.5 ug/mL|
|Immunofluorescence (IF)||2.5 ug/mL|
|Western Blot (WB)||1 ug/mL|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 16 amino acid synthetic peptide near the amino terminus of human TSHZ1|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is A-20 cell lysate.
PA5-34342 can be used with blocking peptide PEP-1385.
The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Antigen NY-CO-33; NY-CO-33; SDCCAG33; Serologically defined colon cancer antigen 3 homolog; Serologically defined colon cancer antigen 33; Teashirt homolog 1; teashirt zinc finger family member 1; Teashirt zinc finger homeobox 1; TSHZ1
Gene Aliases: 5730407I04Rik; CAA; D18Bwg1409e; Kiaa4206; mKIAA4206; Mtsh1; NY-CO-33; SDCCAG33; teashirt1; TSH1; TSHZ1
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