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          • Primary Antibodies ›
          • TSTA3 Antibodies

          Invitrogen

          TSTA3 Polyclonal Antibody

          View all (10) TSTA3 antibodies

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          Cite TSTA3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          TSTA3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          TSTA3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          TSTA3 Antibody (PA5-97779) in ICC/IF

          Immunofluorescent analysis of TSTA3 in Hela cells using a TSTA3 polyclonal antibody (Product # PA5-97779) at a dilution of 1:100. Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibody was used. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
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          TSTA3 Antibody in Immunocytochemistry (ICC/IF)
          TSTA3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TSTA3 Antibody in Western Blot (WB)
          TSTA3 Polyclonal Antibody

          Product Details

          PA5-97779

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:5,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          Assay-Dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human GDP-L-fucose synthase protein (1-314AA)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          3 mg/mL

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2812394

          Target Information

          Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 3-5 epimerase/4-reductase; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; GDP-L-fucose synthase; Protein FX; Red cell NADP(H)-binding protein; short chain dehydrogenase/reductase family 4E, member 1; Short-chain dehydrogenase/reductase family 4E member 1; testis tissue sperm-binding protein Li 45a; tissue specific transplantation antigen 3; tissue specific transplantation antigen P35B; unnamed protein product

          View more View less

          Gene Aliases: FX; GFUS; P35B; SDR4E1; TSTA3

          View more View less

          UniProt ID: (Human) Q13630

          View more View less

          Entrez Gene ID: (Human) 7264

          View more View less

          Function(s)
          catalytic activity protein binding electron carrier activity oxidoreductase activity isomerase activity GDP-4-dehydro-D-rhamnose reductase activity identical protein binding GDP-mannose 3,5-epimerase activity GDP-L-fucose synthase activity
          Process(es)
          T cell mediated cytotoxicity leukocyte cell-cell adhesion nucleotide-sugar biosynthetic process positive regulation of endothelial cell migration GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process positive regulation of endothelial cell-matrix adhesion via fibronectin
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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