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Proteintech
TTC5 Polyclonal Antibody
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Product Details
26112-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TTC5 Fusion Protein Ag23523 (1-348 aa encoded by BC053538)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MMADEEEEV KPILQKLQEL VDQLYSFRDC YFETHSVEDA GRKQQDVRKE MEKTLQQMEE VVGSVQGKAQ VLMLTGKALN VTPDYSPKAE ELLSKAVKLE PELVEAWNQL GEVYWKKGDV AAAHTCFSGA LTHCRNKVSL QNLSMVLRQL RTDTEDEHSH HVMDSVRQAK LAVQMDVHDG RSWYILGNSY LSLYFSTGQN PKISQQALSA YAQAEKVDRK ASSNPDLHLN RATLHKYEES YGEALEGFSR AAALDPAWPE PRQREQQLLE FLDRLTSLLE SKGKVKTKKL QSMLGSLRPA HLGPCSDGHY QSASGQKVTL ELKPLSTLQP GVNSGAVILG KVVFSLTTE (1-348 aa encoded by BC053538 )
Target Information
Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Strap; strap; Stress-responsive activator of p300; Tetratricopeptide repeat protein 5; TPR repeat protein 5; unnamed protein product
Gene Aliases: NEDCAFD; Strap; TTC5
UniProt ID: (Human) Q8N0Z6, (Rat) Q5BK48
Entrez Gene ID: (Human) 91875, (Rat) 305837
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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