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          • Primary Antibodies ›
          • TTLL12 Antibodies

          Invitrogen

          TTLL12 Polyclonal Antibody

          View all (9) TTLL12 antibodies

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          Cite TTLL12 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          TTLL12 Antibody (PA5-76352) in IHC (P)

          Immunohistochemistry analysis of TTLL12 in paraffin-embedded human liver injury. Samples were incubated with TTLL12 polyclonal antibody (Product # PA5-76352) at a dilution of 1:100. Results were magnified with a 40x lens. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TTLL12 Antibody in Western Blot (WB)

          Product Details

          PA5-76352

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein of human TTLL12.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2720079

          Product Specific Information

          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

          Target Information

          TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: dJ526I14.2; Inactive tubulin--tyrosine ligase-like protein 12; KIAA0153; TTL domain protein; ttll12; tubulin tyrosine ligase-like family, member 12; Tubulin--tyrosine ligase-like protein 12; unnamed protein product

          View more View less

          Gene Aliases: BC055368; D430005B17; dJ526I14.2; KIAA0153; RGD1305319; TTLL12

          View more View less

          UniProt ID: (Human) Q14166, (Mouse) Q3UDE2

          View more View less

          Entrez Gene ID: (Human) 23170, (Rat) 300105, (Mouse) 223723

          View more View less

          Function(s)
          nucleotide binding tubulin-tyrosine ligase activity protein binding ATP binding histone H4K20me2 reader activity histone H4K20 trimethyltransferase activity molecular_function
          Process(es)
          immune system process chromatin organization regulation of mitotic cell cycle innate immune response negative regulation of type I interferon-mediated signaling pathway cellular protein modification process biological_process
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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