Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SLEIGLCVNM RSLPWYVPAN PDSFFPRCYS LCTESEQQEF LEDFRRTMAS SILKWVVSHQ SCSRSSRSKP RDQREEAGSS DLSSRQDAEN AEAKLRGLPG QLVDIACKVC QAYLGQLEHE DIDTSADAVE DLTEAEWEDL TQQYYSLVHG DAFISNSRNY FSQCQALLNR ITSVNPQTDI DGLRNIWII
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 59%.
Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: tubulin tyrosine ligase-like family member 8; tubulin tyrosine ligase-like family, member 8; tubulin--tyrosine ligase-like protein 8
Entrez Gene ID: (Human) 164714
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