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Proteintech
TTYH1 Polyclonal Antibody
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Product Details
26973-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TTYH1 Fusion Protein Ag25290 (264-390 aa encoded by BC011347)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EAATAVGLS DFCSNPDPYV LNLTQEETGL SSDILSYYLL CNRAVSNPFQ QRLTLSQRAL ANIHSQLLGL EREAVPQFPS AQKPLLSLEE TLNVTEGNFH QLVALLHCRS LHKDYGAALR GLCEDALE (264-390 aa encoded by BC011347)
Target Information
TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hTTY1; hTTY1s; mTTY1; predicted membrane protein; Protein tweety homolog 1; tweety homolog 1; unnamed protein product; Volume-regulated anion channel subunit TTYH1
Gene Aliases: 4930459B04Rik; 6330408P11Rik; mTTY1; tty; TTY1; TTYH1
UniProt ID: (Human) Q9H313, (Mouse) Q9D3A9, (Rat) P0C5X8
Entrez Gene ID: (Human) 57348, (Mouse) 57776, (Rat) 292597
mitotic cell cycle
cell morphogenesis
ion transport
chloride transport
iron ion transport
cell adhesion
Notch signaling pathway
gene expression
L-glutamate transport
neurogenesis
cell-substrate adhesion
ion transmembrane transport
iron ion transmembrane transport
filopodium assembly
stem cell differentiation
stem cell proliferation
cell-cell adhesion
chloride transmembrane transport
mitotic nuclear division
single organismal cell-cell adhesion
regulation of anion transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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