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Invitrogen
TUB Polyclonal Antibody
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FIGURE: 1 / 6
TUB Antibody (PA5-31164) in ICC/IF
TUB Polyclonal Antibody detects Tub protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: SKNSH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Tub protein stained by TUB Polyclonal Antibody (Product # PA5-31164) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
Product Details
PA5-31164
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Tub. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH, Neuro2A, GL261.
Predicted reactivity: Mouse (92%), Rat (93%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: retinal degeneration 5; tubby bipartite transcription factor; tubby homolog; tubby homologue; Tubby protein; Tubby protein homolog; unnamed protein product
Gene Aliases: Rd5; RDOB; TUB
UniProt ID: (Human) P50607, (Mouse) P50586, (Rat) O88808
Entrez Gene ID: (Human) 7275, (Mouse) 22141, (Rat) 25609
phagocytosis
phagocytosis, recognition
sensory perception of sound
photoreceptor cell maintenance
positive regulation of phagocytosis
response to stimulus
retina development in camera-type eye
receptor localization to nonmotile primary cilium
protein localization to ciliary membrane
protein localization to photoreceptor outer segment
phototransduction
detection of visible light
response to hormone
multicellular organismal macromolecule metabolic process
regulation of G-protein coupled receptor protein signaling pathway
intraciliary transport
protein localization to cilium
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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