Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH, Neuro2A, GL261.
Predicted reactivity: Mouse (92%), Rat (93%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: retinal degeneration 5; tubby homolog; tubby homologue; Tubby protein; Tubby protein homolog
Gene Aliases: Rd5; RDOB; TUB