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Immunogen sequence: LPSFWVSFFA ETGILFPGGT PWPMGSQHSK QHRKPGPLKR GHRRDRRTTR RKYWKEGREI
Highest antigen sequence identity to the following orthologs: Mouse - 27%, Rat - 28%.
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: tubby homolog; tubby homologue; Tubby protein homolog
Gene Aliases: rd5; RDOB; TUB
UniProt ID: (Human) P50607
Entrez Gene ID: (Human) 7275
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