Search
Proteintech
TUBGCP5 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
14620-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TUBGCP5 Fusion Protein Ag6248 (676-1024 aa encoded by BC071560)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ESVTCQTFE LTLRSCLYPH IDKQYLDCCG NLMQTLKKDY RLVEYLQAMR NFFLMEGGDT MYDFYTSIFD KIREKETWQN VSFLNVQLQE AVGQRYPEDS SRLSISFENV DTAKKKLPVH ILDGLTLSYK VPWPVDIVIS LECQKIYNQV FLLLLQIKWA KYSLDVLLFG ELVSTAEKPR LKEGLIHEQD TVAQFGPQKE PVRQQIHRMF LLRVKLMHFV NSLHNYIMTR ILHSTGLEFQ HQVEEAKDLD QLIKIHYRYL STIHDRCLLR EKVSFVKEAI MKVLNLALMF ADGWQAGLGT WRMESIEKME SDFKNCHMFL VTILNKAVCR GSFPHLESLA LSLMAGMEQS (676-1024 aa encoded by BC071560)
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP5 ( gamma-Tubulin complex component 5), also known as TUBGCP5, is a 1, 024 amino acid member of the gamma-Tubulin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior and lower intellectual ability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Gamma-tubulin complex component 5; gamma-tubulin complex component GCP5; GCP-5; tubulin gamma complex associated protein 5; unnamed protein product
Gene Aliases: B130010C12Rik; GCP5; KIAA1899; mKIAA1899; TUBGCP5
UniProt ID: (Human) Q96RT8, (Mouse) Q8BKN5
Entrez Gene ID: (Human) 114791, (Mouse) 233276, (Rat) 308663
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support