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Immunogen sequence: ADAVQDSEMV ELVELEIREL LTEFGYKGEE TPVIVGSALC ALEGRDPELG LKSVQKLLDA VDTYIPVPAR DLEKPFLLPV EAVYSVPGRG TVVTGTLERG ILKKGDECEL LGHSKNIRTV VTGIEMFHKS LERAEAGDNL GALVRGLKRE DLRRGLVMVK PGSIKPHQKV EAQVYILSKE EGGRHKPFVS HFMPVMFSLT WDMACRIILP PEKELAMPGE DLKFNLILRQ PMILEKGQRF TLRDGNRTIG TGLVTNTLAM TEEEKNIKWG; Positive Samples: HT-29, HepG2, HeLa, A-431, Jurkat, Mouse kidney, Mouse liver, Rat kidney, Rat liver; Cellular Location: Mitochondrion
This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.
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Protein Aliases: EF-Tu; Elongation factor Tu, mitochondrial; P43; tufm {ECO:0000250|UniProtKB:P49411}
Gene Aliases: 2300002G02Rik; C76308; C76389; COXPD4; EF-TuMT; EFTU; P43; TUFM
UniProt ID: (Human) P49411, (Mouse) Q8BFR5, (Rat) P85834
Entrez Gene ID: (Human) 7284, (Mouse) 233870, (Rat) 293481
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