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TULP3 Antibody (PA5-53297) in WB
Western blot analysis of TULP3 in control (vector only transfected HEK293T lysate) and TULP3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a TULP3 Polyclonal Antibody (Product # PA5-53297).
Product Details
PA5-53297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TULP3. Recombinant protein control fragment (Product #RP-91604).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2649121
Product Specific Information
Immunogen sequence: TGTSGSATAA QPADNLLGDI DDLEDFVYSP APQGVTVRCR IIRDKRGMDR GLFPTYYMYL EKEENQKIFL LAARKRKKSK TANYLISIDP VDLSREGESY VGK^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 72%.
Target Information
This gene encodes a member of the tubby-like protein (TULP) family. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved C-terminal region of approximately 200 amino acid residues. The human and mouse TULP3 proteins share 69% amino acid sequence identity, with higher identity at the N and C termini than in the central region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Tubby-like protein 3; Tubby-related protein 3
Gene Aliases: TUBL3; TULP3
UniProt ID: (Human) O75386
Entrez Gene ID: (Human) 7289
neural tube closure
regulation of transcription, DNA-templated
G-protein coupled receptor signaling pathway
brain development
regulation of G-protein coupled receptor protein signaling pathway
anterior/posterior pattern specification
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
central nervous system neuron differentiation
embryonic camera-type eye development
embryonic digit morphogenesis
negative regulation of smoothened signaling pathway
embryonic neurocranium morphogenesis
bone development
bronchus morphogenesis
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
ganglion development
receptor localization to nonmotile primary cilium
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
protein localization to photoreceptor outer segment
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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